Patients relieved by Zimmer's hip and knee solutions propelled it to become the market leader. The solutions not only provided pain relief, good quality of life of the patient, but it also helped in restoring mobility for a number of patients. The products like femoral (neck and stem) components, acetabular (cup) components and revision surgery systems are manufactured by Zimmer.
The technique of Metasul Metal-on-Metal articulation and Trabecular Metal technology is used in manufacturing these implants which are capable of providing a good level of friction resulting in faster joint stabilization. But there was a major issue encountered because of the metal grounding on metal as it leads to toxic metal shards being released into the patient's surrounding tissues and bone. Gradually, these toxins have resulted in causing inflammation, infection, a decay of soft tissue and bone, severe pain and many other adverse reactions requiring surgery to remove and replace the implant.
The Food and Drug Administration (FDA) approved Zimmer Durom Acetabular Component (commonly known as Durom Cup) in 2006 for the use of total hip replacement to address the durability and range of motion of the joint. Most of the Zimmer Holdings Inc. came to the market after going through the FDA’s 510(k) clearance process. The young patients with more physical lifestyle were targeted and implanted, and it was observed it lead to serious injuries within a short time.