Prozac (Fluoxetine) manufactured by Eli Lilly is an antidepressant drug of the selective serotonin reuptake inhibitor (SSRI) class. The Food and Drug Administration (FDA) approved Prozac on 29th Dec 1987 and introduced it to the U.S. market in 1988 for treating major depressive disorders, obsessive-compulsive disorder (OCD), panic disorder, bulimia nervosa, and premenstrual dysphoric disorder. Its off-label uses are for a migraine, ADHD, IBS, fibromyalgia, etc.
Patients taking Prozac have experienced various adverse effects resulting in more mental, emotional and physical suffering. Prozac, if used during pregnancy, may result in babies with birth defects including anencephaly, septal defects, damaged hearts or cleft lip or palate.
Patients consuming Prozac complained of various side effects after usage of this anti-depressant drug which includes loss of appetite, nausea, indigestion, excessive sweating, insomnia, sexual problem, and other physical sufferings. That's not all, Prozac has even led to birth defects, suicidal thoughts, and serotonin syndrome.
Various healthcare professionals have voiced concern over the usage of Prozac during pregnancy. Medical studies have associated the use of SSRIs during pregnancy with birth defects. In the year 2006, FDA has issued a warning to doctors about the risk involved in consuming this antidepressant drug during pregnancy. Some women even sued the maker of Prozac as they had used this drug during pregnancy that resulted in birth defects to their children.
It must be noted that Prozac does come with FDA labeled warning on their packet which states the usage of these SSRIs can lead to suicidal thoughts and behavior in adults. FDA initially issued this warning only for children and adolescents, however, now on May 24, 2007, they even mentioned the risk of suicidal thoughts development in adults.
Prozac also comes along with the risk of serotonin syndrome. SSRI drugs are designed to enhance a patient's mood by increasing the level of a chemical known as serotonin in the brain. However, when this chemical developed excessively in the brain, it can lead to restlessness, high blood pressure, confusion, and muscle twitches. These effects are similar to symptoms associated with methamphetamine.
Selective serotonin reuptake inhibitors (SSRIs) are typically used in the treatment of major depressive disorder and anxiety disorders that work by altering the levels of a mood-enhancing chemical called serotonin. The first SSRI introduced in the market was fluoxetine in 1985. SSRIs are indicated in the treatment of major depression, anxiety disorder, panic disorder, social anxiety disorder, social phobia, bulimia nervosa, obsessive-compulsive disorder, personality disorder, premenstrual disorder and posttraumatic panic disorders. Off-label use of SSRI are a migraine, diabetic neuropathy, neurocardiogenic syncope and fibromyalgia. It was noted when pregnant women consume SSRIs, the risk of autism spectrum disorder and birth defects in newborns increased.The Food and Drug Administration (FDA) has issued alerts regarding unreported side effects of Zoloft, Prozac, Paxil, Celexa, Lexapro, most of which have led to litigation against the manufacturers.